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Proteinase 3 : ウィキペディア英語版
Proteinase 3

Proteinase 3 also known as PRTN3 is an enzyme that in humans is encoded by the ''PRTN3'' gene.
== Function ==

PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown, but, in human neutrophils, proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the ''c-ANCA'' (cytoplasmic subtype) class, a type of antibody frequently found in the disease granulomatosis with polyangiitis (formerly known as "Wegener's granulomatosis").

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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